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The 2025 MLS season begins with Messi`s Inter Miami favored to win, alongside exciting match predictions.

The 2025 Major League Soccer season has officially kicked off, featuring 30 teams, including the new San Diego FC. Inter Miami, led by superstar Lionel Messi, is a strong contender for the championship this year.

In the opening matches, LAFC is predicted to secure a 3-1 victory over Minnesota United FC, while Atlanta United FC is expected to dominate CF Montréal with a 3-0 scoreline. FC Cincinnati is favored to edge out the New York Red Bulls 2-1, showcasing their new signings.

Columbus Crew SC and Chicago Fire are anticipated to draw 1-1, as both teams navigate significant changes. D.C. United, despite having MLS Golden Boot winner Christian Benteke, is predicted to fall 1-2 to Toronto FC. Inter Miami is expected to triumph 3-1 against New York City FC, with Messi leading the charge.

Other matches include Orlando City SC vs. Philadelphia Union, predicted to end in a goalless draw, and Austin FC vs. Sporting Kansas City, expected to finish 2-2. FC Dallas is projected to win 3-0 against Houston Dynamo, while Nashville SC and New England Revolution are likely to draw 1-1. San Jose Earthquakes are favored to beat Real Salt Lake 3-0, and Colorado Rapids are expected to edge St. Louis CITY SC 2-1.

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