By half-session, England's Lisowski was leading 4-0 thanks to breaks of 70, 100, 96, and 69.
With runs of 80 and 72, the Belgian made a comeback, but Lisowski's breaks of 63 and 68 cemented the victory.
Lisowski's next opponent in the quarterfinals on Thursday will be either Chinese rookie Zhang Anda or fellow countryman Shaun Murphy.
#snooker #jack